Exacerbation Management
This second section for the treatment of multiple sclerosis (MS) refers to managing exacerbations, which are the sudden flare-up of symptoms, often lasting from one to three months. Intravenous injection (IV) and/or oral steroids are usually prescribed to minimize the effects of an exacerbation and to try to prevent any long-term damage that may be caused by an exacerbation. Exacerbations may be treated at the hospital or in one's home, where a visiting nurse may administer the IV.
Not all of these treatments are approved by the FDA (United States Food & Drug Administration) specifically for the treatment of MS. The drugs listed were compiled by Dr. Jack Burks, MSAA’s chief medical officer.
- Solu-Medrol® (IV methylprednisolone)
- Prednisone
- Decadron® (dexamethasone)
- Medrol® (oral methylprednisolone)
- Plasmapheresis (plasma exchange)*
- Intravenous immunoglobulin (IVIg) therapy*
*Dr. Burks notes that when using these types of therapies for the treatment with MS, the results have been mixed; studies continue to determine the effectiveness of these treatments with MS.
Please note that MSAA does not endorse or recommend any specific drug or treatment. Individuals are advised to consult with a physician about the potential benefits and risks of the different treatment therapies.





